Zopiclone: A Comprehensive Guide


zopiclone is a medication used to treat insomnia, a condition in which a person has difficulty falling asleep or staying asleep. It belongs to a class of drugs known as sedative-hypnotics, which work by slowing down the central nervous system to induce relaxation and drowsiness. Zopiclone is a prescription-only medication and should only be taken under the supervision of a healthcare provider.

Uses of Zopiclone

Zopiclone is primarily used to treat insomnia, but it may also be prescribed for other purposes. Some of the other conditions that may be treated with zopiclone include:

  • Anxiety disorders
  • Depression
  • Sleep disorders associated with medical or psychiatric conditions

How Zopiclone Works

Zopiclone works by enhancing the activity of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. GABA is a chemical messenger that helps to regulate the activity of the nervous system. By increasing the amount of GABA in the brain, zopiclone slows down the activity of the central nervous system, leading to feelings of relaxation and drowsiness.

Dosage and Administration

Zopiclone is available in tablet form and is typically taken once daily, before bedtime. The recommended dose for most zopisign 10mg and zopisign 7.5, although some people may require a higher or lower dose. It is important to take zopiclone exactly as prescribed by a healthcare provider, and not to exceed the recommended dose.

Side Effects

Like all medications, zopiclone may cause side effects in some people. 

most common side effects of zopiclone include:

  • Drowsiness
  • Dizziness
  • Headache
  • Dry mouth
  • Nausea
  • Muscle weakness

Less common side effects of zopiclone may include:

  • Confusion
  • Memory problems
  • Changes in mood or behavior
  • Hallucinations
  • Seizures

If you experience any of these side effects, it is important to contact your healthcare provider immediately.

Precautions and Interactions

Before taking zopiclone, it is important to tell your healthcare provider about any other medications you are taking, including over-the-counter medications and herbal supplements. 

Zopiclone may interact with other medications, such as:

  • Alcohol
  • Narcotic pain medications
  • Antidepressants
  • Antipsychotics
  • Muscle relaxants

Zopiclone may also increase the risk of falls and accidents, especially in older adults or people with impaired coordination. It is important to use caution when driving or operating machinery while taking zopiclone.

Withdrawal and Dependence

Zopiclone can be habit-forming, and regular use may lead to dependence. If zopiclone is taken for an extended period of time, sudden discontinuation may lead to withdrawal symptoms such as anxiety, restlessness, and insomnia. To prevent withdrawal symptoms, it is important to gradually taper off the medication under the guidance of a healthcare provider.

Special Populations

Zopiclone should be used with caution in certain populations, including:

  • Older adults: Zopiclone may increase the risk of falls and confusion in older adults.
  • Pregnant or breastfeeding women: Zopiclone may pass into breast milk and may harm a developing fetus.
  • People with liver or kidney disease: Zopiclone is metabolized by the liver and excreted by the kidneys, so people with liver or kidney disease may require a lower dose.


Taking more zopiclone than prescribed can lead to overdose, which can be life-threatening.

Symptoms of overdose may include:

  • Severe drowsiness
  • Confusion
  • Weakness
  • Difficulty breathing
  • Coma

If you suspect that you or someone else has taken an overdose of zopiclone, it is important to seek medical attention immediately.

Alternatives to Zopiclone

If zopiclone is not effective or causes intolerable side effects, there are other medications that may be used to treat insomnia.

Some of these alternatives include:

  • Benzodiazepines: Benzodiazepines, such as diazepam and lorazepam, are also sedative-hypnotics that enhance the activity of GABA in the brain. However, they are generally more potent and have a higher risk of dependence and withdrawal than zopiclone.
  • Non-benzodiazepine hypnotics: Non-benzodiazepine hypnotics, such as zaleplon and eszopiclone, work in a similar way to zopiclone but may have a different side effect profile.
  • Melatonin agonists: Melatonin agonists, such as ramelteon and tasimelteon, work by mimicking the action of the hormone melatonin, which regulates the sleep-wake cycle. They may be particularly useful for people with insomnia associated with circadian rhythm disorders.

In addition to medication, there are non-pharmacological treatments for insomnia, such as cognitive-behavioral therapy (CBT). CBT is a form of talk therapy that aims to identify and modify the thoughts and behaviors that contribute to insomnia.


Zopiclone is a medication used to treat insomnia and other sleep disorders. It works by enhancing the activity of a neurotransmitter called GABA in the brain, leading to feelings of relaxation and drowsiness. Like all medications, zopiclone may cause side effects in some people and may interact with other medications. It is important to take zopiclone exactly as prescribed and to discuss any questions or concerns with a healthcare provider.

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